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Clinical Trials

Without the use of human volunteers in clinical trials, there would be few or no new medicines or diagnostic and therapeutic technologies. Under strict guidelines there is a constant search for newer, safer and more effective medications and equipment. There are many clinical trials being conducted in Long Island hospitals and other venues, many funded by the federal government. The most comprehensive listing of clinical trials may be found at: clinicaltrials.gov.

Feinstein Institute for Medical Research: Understanding the Immune System in Health and Disease

Volunteers are sought for a study of the human immune system which plays a vital role in maintaining health and protecting against disease by identifying and destroying foreign substances such as bacteria or tumor cells.

By studying immune functions in many people, scientists will be able to determine the range of normal variation for many aspects of the immune system. With a better understanding of normal immune system activity, scientists will then be able to compare and learn more about diseases caused by abnormalities in the immune system such as autoimmune disease and cancer.

Volunteers who participate in the study will also become part of the Feinstein Medical Research Registry, which is a program for individuals who would like to support medical research by participating as a control or comparison subject. Participants in the Registry may be notified about additional studies they may be able to participate in as a comparison subject; however, there is no obligation to participate in any additional studies.

Men and women aged 18 or older, without a history of autoimmune disease, chronic immunodeficiency, or current pregnancy, treatment for cancer, or acute illness are eligible to participate. Participation involves completing a brief health history questionnaire, providing a one-time blood collection and allowing us to contact you about additional studies you want to participate in. Participants will be compensated $25.00 for their time and travel. For more information please contact Mary Keogh, ANP at (516) 562-3491

South Nassau Communities Hospital: Phase III Chemoprevention Trial of Selenium Supplementation in Persons with Resected Stage I Non-Small Cell Lung Cancer

The objective of this study is to evaluate the effectiveness of selenium supplementation (using selenium yeast tablets versus placebo tablets) in reducing the incidence of second lung tumors in persons who have been surgically treated for Stage I non-small cell lung cancer.

For participation patients must be at least 18 years old and must have undergone complete surgical removal (resection) of a confirmed Stage I non-small cell lung cancer.

For more information or to see if one may qualify for this study, call (516) 255-5010 or (516) 632-3302.

Stony Brook University Medical Center: Will a Bipolar Disorder Medicine for Adults Help Children with the Condition?

Researchers in the Child Psychiatry Outpatient Department are evaluating whether an investigational medicine for adult individuals with bipolar disorder (Lamictal) is safe and effective in children with the condition. The study medication is approved by the Food and Drug Administration for use in adults with bipolar I disorder.

The study will test the safety and effectiveness of the investigational medicine versus placebo when added to conventional bipolar medications. Taking the investigational medicine will not interfere with patients continuing their conventional regimens.

All participants must be between ages 10 and 17 years, diagnosed with bipolar I disorder, and currently on a stable medication regimen but still experiencing symptoms. Participants will be required to attend regular study visits at the department for a period of approximately one year. All patient information is kept confidential. Enrolled participants receive specific medical care, including comprehensive psychiatric evaluations, at no cost. There will also be compensation for time and travel.

For more information about the study and enrollment, please call (631) 632-8828.

Winthrop-University Hospital: Investigational Medication for Partial Onset Seizures

Volunteers with partial onset seizures are sought by the Neurology Department to participate in a clinical research study to evaluate the safety and effectiveness of an alternative single therapy investigational medication.

To be eligible, an individual must be 16 to 75 years old, have a diagnosis of partial onset seizures and must be taking one or two other antiepileptic medications. Eligible participants will receive study-related medical examinations, research medication and laboratory tests at no cost while participating in the research study. Compensation for time and travel may also be provided.

For further details, please call the hospital’s Clinical Trials Center at (516) 663-9582 or email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it .