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Clinical Trials

Research is the mother’s milk of new medications, diagnostic and therapeutic technologies. There is a constant research effort to find new, safer and more effective ways of making us a healthier society. While there are many clinical research projects being conducted all over Long Island in different venues, here is just a partial list being performed at Nassau County institutions.


Feinstein Institute for
Medical Research: Do
Combined Drugs for ADHD
Reduce Aggressive Behavior?

The objective is to see whether antipsychotic medicines used in combination with traditional stimulant medicines for Attention Deficit Hyperactivity Disorder work in reducing aggressive behavior.

These combined treatments are common, yet there is no data to show that the combinations are any better than one drug alone. The study is designed to answer that question.

Children with diagnosed ADHD must be between 6 and 12 to be accepted into the study. The researchers are comparing the antipsychotic medicine risperidone (Risperdal) with valproic acid, a mood stabilizer. They are evaluating the efficacy, tolerability and longevity of benefit of these two agents in diminishing aggressive behavior.

For more details, contact Michele Gonen at (718) 470-8487 and in Suffolk, contact Ashley Conway at (631) 632-8317.


South Nassau Communities Hospital: A Randomized
Clinical Trial Comparing Knee Thermal Chondroplasty
Using the Smith & Nephew Glider RF Probe to
Debridement Using a
Mechanical Shaver

The objective of this study is to evaluate two different surgical techniques for treatment of knee cartilage damage. The research study will compare standard treatment using a mechanical shaver to treatment using radiofrequency (RF) energy using the Glider RF Probe.

For more details, information and study criteria for qualifications, call (516) 536- 2800.


Stony Brook University
Medical Center: Helping Heart Failure Patients
Help Themselves

The researchers are conducting a study that tests an educational method to help patients monitor their heart failure symptoms. Patients who can effectively monitor their symptoms can better guide physicians in treating their heart failure that affects more than five million Americans.

If qualified to participate, heart failure patients complete questionnaires about their medical history, symptoms, self-care, and quality of life. All participants will be given a weight scale to keep and a booklet on heart failure self-care.

Participants are followed for one year by telephone. The telephone interviews last 15 to 20 minutes each and are conducted at months1,3, 6,and 12 after enrollment in the study. Each participant will be paid $20 at both 6 and 12 months after the telephone interviews are completed.

For more information or to schedule an appointment for enrollment, please call either (631) 444-3236 or (631) 444-1299.


Winthrop-University Hospital:
Evaluate a New Drug for Sjogren’s Syndrome

The Division of Rheumatology, Allergy & Immunology is seeking volunteers to participate in a clinical research study to test the safety and effiectiveness of an investigational medication used for dry mouth associated with Sjogren’s Syndrome. The purpose of the study is to enhance hydration and relieve the symptoms of dry mouth.

To be eligible for the study, participants must be between 18 and 80 years of age and must have been diagnosed with dry mouth associated with Sjogren’s Syndrome. Eligible participants will receive study-related investigational medication, medical care and laboratory procedures at no cost. Reimbursement will also be provided for time and travel expenses.

For further details and qualifications, please call Winthrop’s Clinical Trials Center at (516) 663-9582 or e-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it .